Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
NF-κB Signaling | NF-kappaB Pathway
DNA polymerases and cancer | Nature Reviews Cancer
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
Science Signaling - The DNA polymerase Pol-kappa endows tumor cells with resistance to the BRAF inhibitor vemurafenib without increasing mutagenesis, according to new research from the White lab. https://fcld.ly/5jaum2s Credit: K. Temprine
Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis
Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance | Science Signaling
DNA Polymerase Kappa Research Products: Novus Biologicals
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ | PLOS ONE
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender - ScienceDirect
Anti-DNA Polymerase Kappa/POLK antibody (ab86076) | Abcam
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells | Biochemistry
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide - ScienceDirect
DNA Polymerase Kappa Antibody (6F2) (H00051426-M01): Novus Biologicals
Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites | PNAS
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity
Inhibition of host NF-kappa-B by virus ~ ViralZone
A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ | PLOS ONE
